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| Click on the
following links to download the slide presentations with speaker notes |
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- Thyroid Dysfunction: Clinical Overview
An overview of thyroid disease, including a review of thyroid function, the epidemiology of thyroid disease in the US, the diagnosis and treatment of thyroid disease, and the clinical consequences of elevated and decreased TSH.
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- Thyroid Dysfunction: Clinical Overview
(for pharmacists)
A discussion for pharmacists on the hypothalamic-pituitary-thyroid axis, the consequences of various forms of thyroid dysfunction, and the diagnosis and treatment of thyroid disease with levothyroxine.
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- Diagnosis and Management of Thyroid Cancer
A review of the major types of thyroid cancer, statistics on recurrence and death after diagnosis, algorithms for treatment, and a discussion of the importance of TSH suppression in patients with thyroid cancer.
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- Clinical Issues in Bioequivalence and Product Substitution
A discussion of issues associated with the prescription of generic products, including FDA determination of bioequivalence and the possible negative clinical consequences of switching to a generic version of levothyroxine, a narrow therapeutic range drug.
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- Levothyroxine Bioequivalence Study M02-417
A synopsis of a study with various doses of levothyroxine which found that the sensitivity of bioavailability measurements did not make adjustment for endogenous baseline T4 levels, so that products deemed bioequivalent could differ as much as 35%.
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- Thyroid
Function and Disease
A review of the function of the thyroid gland and the actions of thyroid hormone, and an overview of thyroid disease states – hypothyroidism and hyperthyroidism – including prevalence, signs, and symptoms.
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- Thyroid Disease Management
A slide presentation on thyroid disease treatment, including recommendations for treating hypothyroidism, hyperthyroidism, and mild thyroid failure, and information on special populations: elderly patients, pregnant women, and those with cardiac disease.
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